Christian McCaffrey exited the game against the Bills early in the second quarter with a knee injury and didn't return.

As the San Francisco 49ers confirmed Christian McCaffrey suffered a likely season-ending injury, his backup, Jordan Mason, ...

Former NFL wideout Ed McCaffrey said it was a tough night after his son, 49ers running back Christian McCaffrey suffered a ...

NFL season was a complete disaster, leading him to make a tough admission about his disappointing year. Christian McCaffrey ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

San Francisco 49ers’ Christian McCaffrey is one of the most exciting talents in NFL. While his professional accomplishments ...

The dark and gloomy 2024 season gets worse for the San Francisco 49ers. On Monday, Kyle Shanahan delivered the worst-case ...

The 49ers — who were already without Trent Williams, Nick Bosa and Deommodore Lenoir — saw Christian McCaffrey leave their ...

San Francisco 49ers star Christian McCaffrey could "potentially" be lost for the season with a knee injury, head coach Kyle ...

There is no timetable for Lawrence's return. Christian McCaffrey and the San Francisco 49ers' season from hell continued in Week 13. The star running back left the team's blowout loss to the Bills ...

Star running back Christian McCaffrey will miss the remainder of the regular season with a PCL injury sustained in the San ...

Fans were excited when the Washington Commanders selected Rice wide receiver Luke McCaffrey in the third round of the 2024 ...