San Francisco 49ers running back Christian McCaffrey was placed on injured reserve for the second time this season after ...

Having suffered a knee injury that landed him on injured reserve during a snowy loss to the Bills on Sunday night, 49ers ...

Christian McCaffrey practiced little and played less this season, seeing action in four games with 65 touches. He is out for the season with his knee injury that will require a six-week recovery.

McCaffrey immediately checked himself out of the game and ran right into the medical tent. The 49ers star RB missed the ...

Christian McCaffrey suffered a PCL injury in the 49ers' Week 13 loss to the Bills. He addressed the injury on social media ...

On Sunday night against the Buffalo Bills, star running back Christian McCaffrey suffered a knee injury that may cost him the ...

McCaffrey should be fine long term, though it's hard to say whether he'd be able to play again this season if the 49ers made ...

49ers head coach Kyle Shanahan told reporters Monday that McCaffrey suffered a posterior cruciate ligament (PCL) injury ...

A spate of injuries has derailed the 49ers' Super Bowl hopes his season, but the bigger question is if their title window has ...

The San Francisco 49ers claimed running back Israel Abanikanda off waivers from the New York Jets on Tuesday, one day after ...

The San Francisco 49ers shored up their suddenly thin running back corps on Tuesday by claiming Israel Abanikanda off waivers from the New York Jets.

The San Francisco 49ers on Tuesday announced how they’d replace running back Christian McCaffrey. In a slew of roster moves ...