San Francisco 49ers running back Jordan Mason is going on injured reserve, head coach Kyle Shanahan announced.

The Highmark Stadium was covered in snow during the Buffalo Bills game against San Francisco 49ers on Sunday (01/12).

Lake-effect snow continued to fall on parts of western New York that were already blanketed with a foot or more over the past ...

In eight season’s San Francisco 49ers tight end George Kittle never played in Buffalo at Highmark Stadium. Despite the loss ...

The heavy lake effect snow prompted the Buffalo Bills to ask fans for help clearing snow out of Highmark Stadium ahead of the ...

San Francisco 49ers quarterback Brock Purdy appears to be making strides in his recovery from a shoulder injury. During the ...

Bills quarterback Josh Allen and head coach Sean McDermott celebrated by making snow angels after Buffalo clinched its fifth ...

Two Erie County Sheriff’s deputies were not injured after they were hit by a truck near Highmark Stadium early Monday, police ...

Here are your top 49ers storylines for Monday, December 2nd.

A Buffalo Bills fan was shirtless in below freezing temperatures and jumping in snow during the team's win over the 49ers.

NBC Sunday Night Football” play-by-play announcer Mike Tirico seems to enjoy calling Buffalo Bills games as much as the ...