San Francisco 49ers defensive end Nick Bosa (hip/oblique) missed his second contest in a row due to hip and oblique injuries.

Head coach Kyle Shanahan reflected on the team's performance against the Bills, previewed the upcoming Week 14 matchup ...

San Francisco 49ers defensive end Nick Bosa (oblique) and offensive tackle Trent Williams (ankle) will not practice on Wednesday, according to Nick Wagoner of ESPN. Bosa has been sidelined over the ...

Nick Bosa is one of several San Francisco 49ers players who will not participate in practice on Wednesday as the team begins ...

The San Francisco 49ers are currently in last place in the division and in danger of missing the playoffs. The team could ...

Bosa (oblique) will not practice Wednesday, Nick Wagoner of ESPN.com reports. Bosa has missed the 49ers' last two games and it appears he may be in danger of missing a third. Considering he hasn't ...

Kyle Shanahan shouldered the blame for the San Francisco 49ers' defensive and overall team struggles this season.

It’s been a rough day – and a rough season - for 49ers fans. Many are depressed over a brutal loss Monday night in Buffalo ...

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

Head Coach Jim Harbaugh meets with the media to discuss the Week 13 victory over the Atlanta Falcons. Outside linebacker Joey ...

The Niners have three MVP-caliber players on offense. All have failed to live up to that standard this season.

Meanwhile, the 5-6 49ers are dealing with massive injury struggles. All-Pro left tackle Trent Williams, Defensive Player of ...