The San Francisco 49ers just kept their season alive with a 38-13 statement win over the Chicago Bears. Here are the 49ers' ...

With both McCaffrey and Jordan Mason on injured reserve as the 49ers head down the stretch, they turned to rookie Isaac ...

Already missing five starters during the blowout loss to the Bills, San Francisco lost star running back Christian McCaffrey ...

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

Christian McCaffrey suffered a PCL injury in the 49ers' Week 13 loss to the Bills. He addressed the injury on social media ...

San Francisco 49ers running back Christian McCaffrey was placed on injured reserve for the second time this season after ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

Christian McCaffrey, at the premature end of a season that started late, too, waxed philosophical in a social media post on ...

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

The 28-year-old took to social media on Wednesday to share a heartfelt message for 49ers fans after his injury-plagued ...

San Francisco’s star running back McCaffrey is sitting on injured reserve once again, with the postseason getting ever nearer ...