Get everything you need to know about how and where to bet on the Week 15 Rams at 49ers Thursday Night Football game.

With their top two options sidelined, the expectation was that rookie Isaac Guerendo would lead the backfield for the ...

San Francisco 49ers running back Christian McCaffrey suffered an an apparent non-contact lower leg injury on Sunday Night ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

San Francisco 49ers star running back Christian McCaffrey receives huge injury update following his exit from the game due to ...

As the San Francisco 49ers confirmed Christian McCaffrey suffered a likely season-ending injury, his backup, Jordan Mason, ...

The 49ers lost running back Christian McCaffrey for the season with a knee injury. His backup, Jordan Mason, will also be ...

The San Francisco 49ers placed running back Christian McCaffrey on injured reserve Tuesday a day after coach Kyle Shanahan ...

The San Francisco 49ers on Tuesday announced how they’d replace running back Christian McCaffrey. In a slew of roster moves ...

Christian McCaffrey suffered a knee injury in the second quarter of “Sunday Night Football” against the Bills.

The San Francisco 49ers on Wednesday continued adjusting to life without running backs Christian McCaffrey and Jordan Mason.

Christian McCaffrey, at the premature end of a season that started late, too, waxed philosophical in a social media post on ...