The Bills (10-2) ended up winning in a rout in a 35-10 final over the 49ers (5-7). That was just the start of it. On a ...

In Sunday's 35-10 win over the San Francisco 49ers, The Buffalo Bills used Alec Anderson as a third tackle on 17 plays, and ...

The Bills and the San Francisco 49ers went head-to-head in freezing conditions Sunday, with Bills fans and staff digging out ...

There's even a chance Guerendo, who pulled his hamstring on the first day of training camp and missed the first two preseason ...

The Great Lakes experienced a surge of activity as arctic air passed over record-warm waters, generating prolific snowfall.

RB Christian McCaffrey suffers potentially season-ending knee injury in loss to Bills, adding to team's struggles.

Josh Allen of the Buffalo Bills and head coach Sean McDermott make snow angels while being interviewed after the Bills ...

AP photographers captured some of the greatest moments from around the sports world last week, including action shots, ...

Donations have flooded in for the cancer survivor who was allegedly pushed down the stairs at Sunday's Bills game, with her ...

Christian McCaffrey may have suffered an isolated PCL tear against the Buffalo Bills, a rare injury that could end his season ...

Josh Allen’s memorable week began with singer and actress Hailey Steinfeld accepting his proposal for marriage and ended with ...

Isaac Guerendo and Will Levis are among UPI senior sports writer Alex Butler's top fantasy football waiver wire priorities ...