The San Francisco 49ers’ dreadful season got worse in Week 13 when running backs Christian McCaffrey and Jordan Mason both ...

San Francisco 49ers running back Christian McCaffrey and top backup Jordan Mason are being placed on injured reserve.

The 49ers are down to one healthy RB, rookie Isaac Guerendo. They will likely elevate Patrick Taylor Jr. from the practice ...

The 24-year-old Guerendo was a fourth-round pick in the 2024 NFL draft. He transferred to Louisville for the 2023 season ...

As the San Francisco 49ers departed Buffalo in the wee hours Monday morning, they were bracing for the possibility that ...

The Detroit Lions won't face Christian McCaffrey in Week 17 this season. The San Francisco 49ers running back injured the PCL ...

San Francisco 49ers star running back Christian McCaffrey will not need surgery on his injured right knee but he will miss ...

Head coach Kyle Shanahan shared the latest injury and team updates emerging from the San Francisco 49ers Week 13 matchup ...

It's going to be another lost season for Christian McCaffrey, but he is not the only San Francisco running back who suffered ...

The San Francisco 49ers entered Sunday night's matchup against the Buffalo Bills at Highmark Stadium without several key ...

The San Francisco 49ers will not have Jordan Mason for the rest of 2024. On Monday, Kyle Shanahan revealed Mason suffered a high ankle sprain in the loss to th ...