Tennessee’s attorney general is set to defend the state’s gender affirming care ban for minors in the U.S. Supreme Court Wednesday against challengers who say the 2023 law endangers children.

The Supreme Court is hearing arguments Wednesday in just its second major transgender rights case, a challenge to a Tennessee law that bans gender-affirming care for minors

The Supreme Court is set to hear oral arguments Wednesday over Tennessee’s law banning transition-related medical care for minors.

More than 20 states have moved to restrict gender-affirming care for youth. Now, the high court will weigh in on Tennessee’s law, and a decision could have wider implications.

The Supreme Court will consider if states can keep transgender adolescents from puberty blockers and hormone therapy, a major culture war flashpoint.

On Wednesday, the U.S. Supreme Court will hear the biggest transgender rights case in its history. The decision in United States v. Skrmetti has the potential to be a seismic one.